Affective disorders, antidepressant drugs and brain metabolism
نویسندگان
چکیده
منابع مشابه
Affective Disorders and Antidepressant Drugs
Affective disorders are a group of psychiatric diseases that can affect an individual at any given age. Also called mood disorders, they can be distinguished into two different types: major depressive disorder, also called major depression, and bipolar disorder, which is known as manic depression. People affected by major depression most often have a low mood, and are consistently in a state of...
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As it is the case in other psychiatric disorders, etiopathogenic hypotheses of depression have chiefly been shaped by the fortuitous discovery of antidepressive drugs. Reciprocally, these hypotheses have largely influenced later innovation in therapeutic drugs. In this paper, we aimed to study the development of pharmacological treatments through the different neurobiological and molecular mode...
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An enhancement of neurotransmission of serotonin (5-HT), noradrenaline, or both, underlies the antidepressant response associated with most agents presently available to treat major depression. With respect to the 5-HT system, antidepressant drugs exert immediate effects on some neuronal elements controlling overall transmission, but it is the gradual changes in neuronal responses to such treat...
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THE LANCET Neurology Vol 1 June 2002 http://neurology.thelancet.com 80 If you respond to the question “what is apathy?” by saying “I don’t know and I don’t care”, you’ve got the correct answer. But if you didn’t get this joke, you may be suffering from impaired humour appreciation, according to research presented at this year’s Rotman Research Institute Conference (Toronto, ON, Canada; March 25...
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Most reports of drug treatment for obsessivecompulsive neurosis concern one tricyclic antidepressant, namely clomipramine. Early suggestions that the drug might be valuable in this condition were based on uncontrolled and/or short-term studies over only a few weeks (Fernandez and Lopez-Ibor, 1967; Beaumont, 1973; Capstick, 1975; Ananth et al., 1978). A recent controlled study with long-term fol...
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ژورنال
عنوان ژورنال: Molecular Psychiatry
سال: 2003
ISSN: 1359-4184,1476-5578
DOI: 10.1038/sj.mp.4001353